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Datelliptium chloride hydrochloride
CAS No. 157000-76-5
Datelliptium chloride hydrochloride( —— )
Catalog No. M20926 CAS No. 157000-76-5
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1368 | Get Quote |
|
| 10MG | 1782 | Get Quote |
|
| 25MG | 2673 | Get Quote |
|
| 50MG | 3573 | Get Quote |
|
| 100MG | 4977 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDatelliptium chloride hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionDatelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
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DescriptionDatelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
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In VitroDatelliptium chloride hydrochloride shows cytotoxic effects after 2 hours of treatment in suspension and primary cultures of rat hepatocytes.
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In VivoDatelliptium chloride hydrochloride has broad antitumor activity against solid tumors of mice in vivo.Datelliptium chloride hydrochloride (170 mg/kg; i.v; for 12 days) exhibits a high degree of antitumor activity at early staged disease.Datelliptium chloride hydrochloride is selectively cytotoxic for solid tumors over leukemia L1210. Animal Model:Mice, colon adenocarcinoma early staged disease model Dosage:170 mg/kg Administration: Intravenous injection, for 12 days Result:Showed potent activity against colon adenocarcinoma.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number157000-76-5
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Formula Weight434.4
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Molecular FormulaC23H29Cl2N3O
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Purity>98% (HPLC)
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Solubility——
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SMILESCCN(CC)CC[n+]1ccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c2c1.Cl.[Cl-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mucci-Lorusso P Polin L Biernat L A et al. Activity of datelliptium acetate (NSC 311152; SR 95156A) against solid tumors of mice[J]. Investigational New Drugs 1990 8(3):253-261.
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